A Postdoctoral position is open in the laboratory of Yingfeng Deng in the Department of Diabetes and Cancer Metabolism at the City of Hope Beckman Research Institute. The Deng laboratory studies the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes and cancer.
Work in the lab utilizes both genetically engineered mouse models and in vitro systems. A combination of state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches is currently used in the lab. Following up with the new paradigm revealed about uridine metabolism by Drs. Deng and Scherer (Science, 2017), the Deng lab is currently focusing on three areas: 1) the role of uridine in the progression of obesity and diabetes. 2) the physiology of uridine in bile and nutrient absorption. 3) the regulation of uridine homeostasis by ER stress and its relevance to breast cancer.
We seek an independent and highly motivated candidate interested in studying the molecular, cellular, and metabolic mechanisms leading to obesity, diabetes, and cancer. Expertise in using mouse models to study metabolic diseases is preferred.
For a complete list of Publications please visit here:
Your qualifications should include:
· Ph.D. and/or M.D. degree in life or biomedical sciences or a related discipline is required.
· Experience in basic molecular biology skills.
· Experience in animal models and lipid metabolism.
· Experience in metabolomics and liver physiology.
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